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SGTL2iは黄斑浮腫低下、GLP-1は網膜症増加と関連?

Risk of diabetic retinopathy and diabetic macular oedema with sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists in type 2 diabetes: a real-world data study from a global federated database. Diabetologia. 2024 Apr 8. doi: 10.1007/s00125-024-06132-5. Epub ahead of print. PMID: 38584180.

Diabetologia

観察研究

インスリン治療中200万人2型DM200万人後向き

SGLT2iは DM黄斑浮腫 HR 0.83 (0.78-0.89)を低下
GLP-1は 網膜症HR 1.30(1.26-1.35)とリスク上昇

ただし後向きの研究

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