SGLT2阻害薬で痛風発作が減少

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SGLT2阻害薬で痛風発作が減少

Serum uric acid lowering and effects of sodium-glucose cotransporter-2 inhibitors on gout: A meta-analysis and meta-regression of randomized controlled trials. Diabetes Obes Metab. 2023 Sep;25(9):2697-2703. doi: 10.1111/dom.15157. Epub 2023 Jun 19. PMID: 37334516.

23/6/19

Diabetes Obes Metab

Pubmed

メタ解析, 介入試験

DAPA, CANVAS, EMPA etcのメタ解析。
痛風発作/尿酸降下薬開始の複合アウトカムはSGLT2阻害薬 vs プラセボでハザード比0.55 (0.45-0.67)と大幅に減少。