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SGLT2+DPP4i、食事負荷試験で評価

β-Cell Function, Incretin Effect, and Glucose Kinetics in Response to a Mixed Meal in Patients With Type 2 Diabetes Treated With Dapagliflozin Plus Saxagliptin. Diabetes Care. 2024 Apr 23:dc232051. doi: 10.2337/dc23-2051. Epub ahead of print. PMID: 38652656.

24/4/23

Diabetes Care

介入試験

2型DM45人(58歳、BMI 30.7、Met内服)
ダパ10mg+サキサ5mg vs ダパのみ vs サキサのみ4週後混合食事負荷試験

平均血糖 -91 vs -53 vs -42
GLP-1平均もダパ+サキサ>サキサ、ダパ単独

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